Category Archives: Research

Lincoln to train new generation of scientists to detect diseases through retinal imaging

A multi-million European project aimed at combating some of the EU’s most prevalent chronic medical conditions is being led by academics at the University of Lincoln.
The REtinal Vascular Modelling, Measurement and Diagnosis (REVAMMAD) project aims to train a new generation of interdisciplinary scientists for the academic, clinical and industrial sectors, and to trigger a new wave of biomedical interventions.
PhD students will be trained by some of the EU’s leading academics and practitioners to further advances in diagnosis, prognosis and prevention of diseases such as diabetes, hypertension, stroke and coronary heart disease and retinal diseases.
Funded by the European Union’s 7th Framework (FP7) Marie Curie Initial Training Network programme, the University of Lincoln has been awarded 900,000 euros from the 3.8 million euro budget to lead the project and to develop retinal imaging and measurement training and research.
The University’s School of Computer Science has a strong track record in retinal image processing, having developed techniques to support automated diagnosis of retinal diseases such as diabetic retinopathy, which can eventually lead to blindness, and new model-based methods for vascular segmentation (image processing of the blood vessels).
The retina provides a unique window into the circulatory system (vasculature) making it an appropriate organ for diagnostic purposes, even for vascular diseases primarily affecting other organs.
Further research into measuring subtle changes in this area will enable the risk of conditions developing to be detected and tracked non-invasively through routine procedures such as standard eye tests at opticians.
Along with partners in the UK, France, Germany, Denmark, Italy and Greece, academics at the University of Lincoln will create a cohort of young researchers able to effectively translate the latest vascular modelling theory and computerised image analysis techniques into effective disease interventions.
Professor Andrew Hunter, Pro Vice Chancellor and Head of College of Science, is the project originator and coordinator and has ten years’ experience in retinal imaging.
He said: “The vasculature plays a key role in chronic medical conditions that account for an increasing proportion of EU member state healthcare costs, including Alzheimer’s, diabetes, stroke and coronary heart disease. These issues have ignited considerable interest in computerised analysis of vascular images, to support scientific enquiry, diagnosis, prognosis and screening. However, until now research has been fragmented. There is therefore a clear need to establish a research community that integrates modelling, measurement and clinical investigation. This requires the training of a community of interdisciplinary experts with the scientific and mathematical expertise to determine how physiological changes can affect the vasculature, the computer vision skills to detect measurements that are correlated to such changes, and the medical expertise to relate these to effective prognosis and diagnosis. We therefore brought together the REVAMMAD project to provide a generation of experts with a unique blend of skills uniting theory, modelling, measurement and decision support, laying the ground work for improved retinal research in the next generation.”
The Initial Training Network (ITN) includes clinicians, hemodynamic (blood movement) theorists, physiologists, imaging experts (retinal and other major vascular systems) pharmacologists and healthcare/bioinformatics companies.
The PhD students will be trained through one common basic scientific course, several blocks of additional modules, plus individual on-site and on-the-job experience at the host partner but also during workshops and summer schools. The breadth of training would not be possible without a European approach because no individual partner or country has the full range of desired expertise or training courses.
Commenting on the ITN, Prof Hunter added: “The training programme will provide facilities that can accommodate any type of PhD student. It will give students the opportunity to learn and develop state of the art techniques and methodologies while working across disciplines. This will help to integrate research around an ambitious programme that will establish a clear EU lead. Improved screening, prognosis and diagnosis for multiple age-related conditions will have a significant impact on health-care costs and quality of life.”
David Steel, Consultant Ophthalmologist at Sunderland Eye Infirmary, a clinical partner in the project, said: “We are excited at the potential enhanced image analysis of the retinal vasculature could offer in terms of earlier diagnosis of both systemic and ophthalmic diseases. Retinal photography is a simple test offered by high street opticians around the country – potentially we could extract a great deal more important information from these images than we currently do and in turn  improve our understanding and management of patients with a range of serious diseases.”

Outstanding Paper award for Cummins Generator Technologies sponsored project

 We all want the machines we use to ‘last’. The $64,000 question is for how long?

“Inevitably, most customers accept that ‘time-expired’ parts will ultimately fail in service but the problems start when components fail ‘early’. A sudden spate of warranty claims can be a nightmare for manufacturers and customers alike, and dealing with them is an expensive and time-consuming business. Obviously, the answer is to make sure it doesn’t fail prematurely by ensuring the highest quality levels. But isn’t there a limit to how much companies can, or should spend on product quality?”

These are the opening lines from an article in Generating Insight, the Cummins Generator Technologies magazine. It discusses the findings from a recent research project funded by Cummins Generator Technologies and undertaken by a Masters student from the School of Computer Science. The student not only presented his research at a top international conference in Thailand, but even won the conference’s “Outstanding Paper Award” for his findings.

Sebastian Olejnik, ICQR2011 Outstanding Paper Award
Sebastian Olejnik, ICQR2011 Outstanding Paper Award

Sebastian Olejnik, a Masters student supervised by Dr Bashir Al-Diri of the School of Computer Science at the University of Lincoln investigated the material and part selection process and its effects on customer satisfaction and business profit. The authors showed that customer objectives are to get a product that at least satisfies their functional requirements and to have a high Quality Price Ratio; meanwhile, business objectives are to earn maximum possible profits and provide a product that at least satisfies customer requirements. All these objectives were combined for an optimal part selection process which needs to start with a reliability analysis to exclude parts and materials below minimum customer reliability standards.

Head of School Dr David Cobham said “The work is an example of the University’s concept of ‘student as producer’ where the students apply the theory they have learned and are encouraged develop ideas of their own. Students of the School of Computer Science have previously succeeded in getting their papers accepted at academic conferences in places as far afield as China and the USA and they have all been funded to travel and present their work. Sebastian was delighted to discover on arriving at the prestigious International Conference on Quality and Reliability in Bangkok that he had won the award which was presented to him at the Conference Dinner.”

“Learn To Lead” on Italian TV

The Social Computing Research Centre which is within the School of Computer Science has been working on a collaborative serious game development project called “Learn To Lead”. Learn To Lead (L2L), which is funded by the European Union Lifelong Learning Programme, aims to deliver training to SME’s in the field of leadership and management development.

L2L gets exposure on RAI, Italy's main broadcaster.
Along with academic and industrial partners from Italy, Spain, and France, academics from the School worked in particular upon the game design phase of the project, which is nearing the completion of its two year development. The project recently enjoyed coverage on Italy’s national TV channel, RAI.

A more in depth look at the L2L project will be posted in the near future.

Research Spotlight: Honda’s ‘Power of Minds’ event

Dr Ben Kirman was recently invited by Honda to attend their ‘Dream Factory’ hack day initiative. Hosted at the Guardian offices and organised by Rewired State, the hack saw 23 developers from across the country feverishly developing prototypes and concepts based on the brief supplied by Honda.

The brief was based on the brand message for the new Honda Civic, which is “If we never venture into the unknown, how do we get anywhere new?”, along with “The Power of Dreams” and the four key attributes of “Quality, Technology, Design and Evolution”.

Ben worked on two projects during the event: ‘Corridor of Dreams’, an art installation that detects individuals as they move through a corridor, and which then renders a ‘dream’ for that individual, and ‘Get Lost’, an app which literally took the Honda Civic message of “If we don’t venture into the unknown, how do we get anywhere new?”.

Ben’s ‘Get Lost’ creation was selected as a winner of its ‘Evolution’ category, and which is going to be part of a Guardian readers vote for a further prize!

Read more about Ben’s experience and the apps at the Honda event over at the LiSc blog.